If you’ve been researching advanced weight loss options, you’ve probably come across two popular tools: GLP-1 medications (like semaglutide) and growth hormone-releasing peptides (like Tesamorelin or Sermorelin). But what’s the difference — and which is better for your goals?
What Are GLP-1s?
GLP-1 agonists (like semaglutide) help regulate blood sugar, curb appetite, and slow digestion. They’re powerful tools for weight loss, especially for those struggling with insulin resistance or metabolic slowdowns. Clients often experience a significant drop in cravings and portion sizes, making it easier to stick with healthier habits.
What Are Growth Hormone-Releasing Peptides?
Peptides like Tesamorelin or Semorelin work differently. Instead of curbing appetite, they stimulate your body’s natural growth hormone production — helping to reduce visceral fat, support lean muscle, and improve recovery. These are popular for clients who want to lose stubborn belly fat without sacrificing muscle tone — a common issue with calorie-cutting alone.
GLP-1 vs. GHRPs: What’s the Main Difference?
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✅ GLP-1s: Great for appetite control, weight loss, blood sugar balance.
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✅ Tesamorelin/Semorelin: Best for improving body composition, preserving muscle, and targeting deep belly fat.
Depending on your goals and lab results, your provider may recommend one or a combination — always customized for you.
How Our Program Keeps You Safe
At Spa Sydell, every client starts with a comprehensive wellness consult, InBody scan, and bloodwork to find the safest, most effective approach. From there, we build a custom plan that may include peptides, nutrition support, exercise guidance, and monthly check-ins to ensure you’re seeing results safely — and sustainably.
Which Is Right for You?
The best option depends on your unique body, lifestyle, and goals. Whether you’re focused on significant weight loss or fine-tuning body composition, our team will help you choose the safest, most effective path forward.